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Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain

RATIONALE: Vortioxetine is a novel multimodal antidepressant that is a 5-HT(1B) receptor partial agonist, a 5-HT(1A) receptor agonist, an inhibitor of the serotonin (5-HT) transporter, and a 5-HT(1D), 5-HT(3), and 5-HT(7) receptor antagonist in vitro. In vivo studies have shown that vortioxetine enh...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: El Mansari, Mostafa, Lecours, Maurice, Blier, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464372/
https://ncbi.nlm.nih.gov/pubmed/25665528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3870-9
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