Chitosan grafted methoxy poly(ethylene glycol)-poly(ε-caprolactone) nanosuspension for ocular delivery of hydrophobic diclofenac

This study aimed to develop a cationic nanosuspension of chitosan (CS) and methoxy poly(ethylene glycol)-poly(ε-caprolactone) (MPEG-PCL) for ocular delivery of diclofenac (DIC). MPEG-PCL-CS block polymer was synthesized by covalent coupling of MPEG-PCL with CS. The critical micelle concentration of...

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Pubblicato in:Sci Rep
Autori principali: Shi, Shuai, Zhang, Zhaoliang, Luo, Zichao, Yu, Jing, Liang, Renlong, Li, Xingyi, Chen, Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464308/
https://ncbi.nlm.nih.gov/pubmed/26067670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11337
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