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Targeting phosphatidylinositol-3-kinase pathway for the treatment of Philadelphia-negative myeloproliferative neoplasms

Myeloproliferative neoplasms (MPN) are a diverse group of chronic hematological disorders that involve unregulated clonal proliferation of white blood cells. Sevearl of them are associated with mutations in receptor tyrosine kinases or cytokine receptor associated tyrosine kinases rendering them ind...

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Publicat a:Mol Cancer
Autors principals: Pandey, Ruchi, Kapur, Reuben
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464249/
https://ncbi.nlm.nih.gov/pubmed/26062813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0388-z
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