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Tumor-induced loss of mural Connexin 43 gap junction activity promotes endothelial proliferation

BACKGROUND: Proper functional association between mural cells and endothelial cells (EC) causes EC of blood vessels to become quiescent. Mural cells on tumor vessels exhibit decreased attachment to EC, which allows vessels to be unstable and proliferative. The mechanisms by which tumors prevent prop...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Principais autores: Choudhary, Mayur, Naczki, Christine, Chen, Wenhong, Barlow, Keith D., Case, L. Douglas, Metheny-Barlow, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464240/
https://ncbi.nlm.nih.gov/pubmed/26002762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1420-9
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