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Tumor-induced loss of mural Connexin 43 gap junction activity promotes endothelial proliferation
BACKGROUND: Proper functional association between mural cells and endothelial cells (EC) causes EC of blood vessels to become quiescent. Mural cells on tumor vessels exhibit decreased attachment to EC, which allows vessels to be unstable and proliferative. The mechanisms by which tumors prevent prop...
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| Publicado no: | BMC Cancer |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464240/ https://ncbi.nlm.nih.gov/pubmed/26002762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1420-9 |
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