Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis

BACKGROUND: Getting access to authentic human drug metabolites is an important issue during the drug discovery and development process. Employing recombinant microorganisms as whole-cell biocatalysts constitutes an elegant alternative to organic synthesis to produce these compounds. The present work...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Geier, Martina, Bachler, Thorsten, Hanlon, Steven P, Eggimann, Fabian K, Kittelmann, Matthias, Weber, Hansjörg, Lütz, Stephan, Wirz, Beat, Winkler, Margit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464233/
https://ncbi.nlm.nih.gov/pubmed/26062974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0262-0
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