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Kissing loop interaction in adenine riboswitch: insights from umbrella sampling simulations

INTRODUCTION: Riboswitches are cis-acting regulatory RNA elements prevalently located in the leader sequences of bacterial mRNA. An adenine sensing riboswitch cis-regulates adeninosine deaminase gene (add) in Vibrio vulnificus. The structural mechanism regulating its conformational changes upon liga...

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Bibliografski detalji
Izdano u:BMC Bioinformatics
Glavni autori: Di Palma, Francesco, Bottaro, Sandro, Bussi, Giovanni
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464220/
https://ncbi.nlm.nih.gov/pubmed/26051557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S9-S6
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