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Preferential Amplification of Pathogenic Sequences

The application of next generation sequencing (NGS) technology in the diagnosis of human pathogens is hindered by the fact that pathogenic sequences, especially viral, are often scarce in human clinical specimens. This known disproportion leads to the requirement of subsequent deep sequencing and ex...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Ge, Fang, Parker, Jayme, Chul Choi, Sang, Layer, Mark, Ross, Katherine, Jilly, Bernard, Chen, Jack
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464073/
https://ncbi.nlm.nih.gov/pubmed/26067233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11047
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