PPAR-Alpha Agonist Used at the Acute Phase of Experimental Ischemic Stroke Reduces Occurrence of Thrombolysis-Induced Hemorrhage in Rats

The impact of fenofibrate, a peroxisome proliferator-activated receptor-alpha (PPAR-α) agonist, on the risk of thrombolysis-induced hemorrhage during the acute phase of stroke in a rat model of stroke was studied. One-hour middle cerebral artery occlusion followed by thrombolysis with tissue plasmin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PPAR Res
Hauptverfasser: Gautier, Sophie, Ouk, Thavarak, Pétrault, Maud, Pétrault, Olivier, Bérézowski, Vincent, Bordet, Régis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464007/
https://ncbi.nlm.nih.gov/pubmed/26106408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/246329
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