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Effect of γ-Cyclodextrin Inclusion Complex on the Absorption of R-α-Lipoic Acid in Rats

R-α-lipoic acid (RLA) is an endogenous organic acid, and works as a cofactor for mitochondrial enzymes and as a kind of antioxidant. Inclusion complexes of RLA with α-, β- or γ-cyclodextrins (CD) were prepared and orally administered as a suspension to rats. Among them, RLA/γ-CD showed the highest p...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Uchida, Ryota, Iwamoto, Kosuke, Nagayama, Suetada, Miyajima, Atsushi, Okamoto, Hinako, Ikuta, Naoko, Fukumi, Hiroshi, Terao, Keiji, Hirota, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463635/
https://ncbi.nlm.nih.gov/pubmed/25946345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160510105
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