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Association between PDCD1 Gene Polymorphisms and Risk of Systemic Lupus Erythematosus in Three Main Ethnic Groups of the Malaysian Population

The programmed cell death 1 (PDCD1) gene encodes for the PD-1 (programmed death 1) molecule, which negatively regulates self-reactive T- and B-cells in the maintenance of peripheral tolerance. A previous report had shown the development of lupus-like phenotypes in PD-1-deficient C57BL/6 mice, was su...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Mol Sci
मुख्य लेखकों: Chua, Kek Heng, Lian, Lay Hoong, Sim, Xiu Jia, Cheah, Tien Eang, Lau, Tze Pheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463618/
https://ncbi.nlm.nih.gov/pubmed/25938972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16059794
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