Gastrin-stimulated Gα(13) Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells

The guanine nucleotide exchange factor Rgnef (also known as ArhGEF28 or p190RhoGEF) promotes colon carcinoma cell motility and tumor progression via interaction with focal adhesion kinase (FAK). Mechanisms of Rgnef activation downstream of integrin or G protein-coupled receptors remain undefined. In...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Masià-Balagué, Miriam, Izquierdo, Ismael, Garrido, Georgina, Cordomí, Arnau, Pérez-Benito, Laura, Miller, Nichol L. G., Schlaepfer, David D., Gigoux, Véronique, Aragay, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463461/
https://ncbi.nlm.nih.gov/pubmed/25922072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.628164
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