Maternal and Zygotic Sphingosine Kinase 2 Are Indispensable for Cardiac Development in Zebrafish

Sphingosine 1-phosphate (S1P) is synthesized from sphingosine by sphingosine kinases (SPHK1 and SPHK2) in invertebrates and vertebrates, whereas specific receptors for S1P (S1PRs) selectively appear in vertebrates, suggesting that S1P acquires novel functions in vertebrates. Because the developmenta...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Hisano, Yu, Inoue, Asuka, Okudaira, Michiyo, Taimatsu, Kiyohito, Matsumoto, Hirotaka, Kotani, Hirohito, Ohga, Rie, Aoki, Junken, Kawahara, Atsuo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463432/
https://ncbi.nlm.nih.gov/pubmed/25907554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634717
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