Pharmacokinetic study of conventional sorafenib chemoembolization in a rabbit VX2 liver tumor model

PURPOSE: Use of oral sorafenib, an antiangiogenic chemotherapeutic agent for hepatocellular carcinoma (HCC), is limited by an unfavorable side effect profile. Transarterial chemoembolization (TACE) employs targeted intravascular drug administration, and has potential as a novel sorafenib delivery me...

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Udgivet i:Diagn Interv Radiol
Main Authors: Parvinian, Ahmad, Casadaban, Leigh C., Hauck, Zane Z., van Breemen, Richard B., Gaba, Ron C.
Format: Artigo
Sprog:Inglês
Udgivet: Turkish Society of Radiology 2015
Fag:
Interventional Radiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463267/
https://ncbi.nlm.nih.gov/pubmed/25835078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5152/dir.2014.14394
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