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Wnt ligand–dependent activation of the negative feedback regulator Nkd1

Misregulation of Wnt signaling is at the root of many diseases, most notably colorectal cancer, and although we understand the activation of the pathway, we have a very poor understanding of the circumstances under which Wnt signaling turns itself off. There are numerous negative feedback regulators...

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Publicat a:Mol Biol Cell
Autors principals: Larraguibel, Jahdiel, Weiss, Alexander R. E., Pasula, Daniel J., Dhaliwal, Rasmeet S., Kondra, Roman, Van Raay, Terence J.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462952/
https://ncbi.nlm.nih.gov/pubmed/25904337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-12-1648
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