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Phospholipase C γ1 regulates early secretory trafficking and cell migration via interaction with p115

The role of early secretory trafficking in the regulation of cell motility remains incompletely understood. Here we used a small interfering RNA screen to monitor the effects on structure of the Golgi apparatus and cell migration. Two major Golgi phenotypes were observed—fragmented and small Golgi....

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Publicado en:Mol Biol Cell
Autores principales: Millarte, Valentina, Boncompain, Gaelle, Tillmann, Kerstin, Perez, Franck, Sztul, Elizabeth, Farhan, Hesso
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462944/
https://ncbi.nlm.nih.gov/pubmed/25904324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-03-0178
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