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Understanding the pathophysiological mechanisms in the pediatric non-alcoholic fatty liver disease: The role of genetics

Classically, the non-alcoholic fatty liver disease (NAFLD) physiopathology and progression has been summarized in the two hits hypothesis. The first hit is represented by the action of hyperinsulinemia and insulin resistance, accompanying obesity, that leads to liver steatosis increasing the absolut...

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Détails bibliographiques
Publié dans:World J Hepatol
Auteurs principaux: Marzuillo, Pierluigi, Grandone, Anna, Perrone, Laura, Miraglia del Giudice, Emanuele
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462683/
https://ncbi.nlm.nih.gov/pubmed/26085904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v7.i11.1439
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