Caffeine increases striatal dopamine D(2)/D(3) receptor availability in the human brain

Caffeine, the most widely consumed psychoactive substance in the world, is used to promote wakefulness and enhance alertness. Like other wake-promoting drugs (stimulants and modafinil), caffeine enhances dopamine (DA) signaling in the brain, which it does predominantly by antagonizing adenosine A(2A...

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Bibliographic Details
Published in:Transl Psychiatry
Main Authors: Volkow, N D, Wang, G-J, Logan, J, Alexoff, D, Fowler, J S, Thanos, P K, Wong, C, Casado, V, Ferre, S, Tomasi, D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462609/
https://ncbi.nlm.nih.gov/pubmed/25871974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.46
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