Alternative polyadenylation is associated with lower expression of PABPN1 and poor prognosis in non-small cell lung cancer

Alternative polyadenylation (APA), which induces shortening of the 3′UTR, is emerging as an important phenomenon in gene regulation. APA is involved in development, cancer and cell proliferation. APA may lead to disruption of microRNA-mediated gene silencing in cancer cells via detachment of microRN...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Ichinose, Junji, Watanabe, Kousuke, Sano, Atsushi, Nagase, Takahide, Nakajima, Jun, Fukayama, Masashi, Yatomi, Yutaka, Ohishi, Nobuya, Takai, Daiya
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462401/
https://ncbi.nlm.nih.gov/pubmed/24975429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12472
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