Inhibition of fibroblast growth factor receptor 2 attenuates proliferation and invasion of pancreatic cancer

The alternative splicing of the extracellular domain of fibroblast growth factor receptor (FGFR)-2 generates the IIIb and IIIc isoforms. Expression of FGFR-2 IIIb correlates with vascular endothelial growth factor-A (VEGF-A) expression and venous invasion of pancreatic ductal adenocarcinoma (PDAC)....

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Matsuda, Yoko, Yoshimura, Hisashi, Suzuki, Taeko, Uchida, Eiji, Naito, Zenya, Ishiwata, Toshiyuki
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462390/
https://ncbi.nlm.nih.gov/pubmed/24975163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12470
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