Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment

Recently, we reported that human leukocyte antigen (HLA) class I expression is predominantly regulated by the mitogen-activated protein kinase (MAPK) pathway as one of the oncogenic regulations of HLA class I expression. In the present study, we examined mechanisms of how HLA class I and PD-L1 are r...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Mimura, Kousaku, Kua, Ley-Fang, Shiraishi, Kensuke, Kee Siang, Lim, Shabbir, Asim, Komachi, Mayumi, Suzuki, Yoshiyuki, Nakano, Takashi, Yong, Wei-Peng, So, Jimmy, Kono, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462358/
https://ncbi.nlm.nih.gov/pubmed/25154680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12503
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