Phase-1 study of abiraterone acetate in chemotherapy-naïve Japanese patients with castration-resistant prostate cancer

Persistent androgen synthesis under castration status in adrenal gland, testes and tumor cells is thought to be one of the major causes of development and progression of castration-resistant prostate cancer (CRPC). Abiraterone acetate (AA), the prodrug of abiraterone, which is an inhibitor of androg...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Matsubara, Nobuaki, Uemura, Hiroji, Fukui, Iwao, Niwakawa, Masashi, Yamaguchi, Akito, Iizuka, Koho, Akaza, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462344/
https://ncbi.nlm.nih.gov/pubmed/25117615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12496
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