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Phase-1 study of abiraterone acetate in chemotherapy-naïve Japanese patients with castration-resistant prostate cancer

Persistent androgen synthesis under castration status in adrenal gland, testes and tumor cells is thought to be one of the major causes of development and progression of castration-resistant prostate cancer (CRPC). Abiraterone acetate (AA), the prodrug of abiraterone, which is an inhibitor of androg...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Matsubara, Nobuaki, Uemura, Hiroji, Fukui, Iwao, Niwakawa, Masashi, Yamaguchi, Akito, Iizuka, Koho, Akaza, Hideyuki
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462344/
https://ncbi.nlm.nih.gov/pubmed/25117615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12496
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