Expression and functional characterisation of System L amino acid transporters in the human term placenta

BACKGROUND: System L transporters LAT1 (SLC7A5) and LAT2 (SLC7A8) mediate the uptake of large, neutral amino acids in the human placenta. Many System L substrates are essential amino acids, thus representing crucial nutrients for the growing fetus. Both LAT isoforms are expressed in the human placen...

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Gaccioli, Francesca, Aye, Irving L. M. H., Roos, Sara, Lager, Susanne, Ramirez, Vanessa I., Kanai, Yoshikatsu, Powell, Theresa L., Jansson, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462079/
https://ncbi.nlm.nih.gov/pubmed/26050671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-015-0054-8
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