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Pharmacokinetics of tramadol following intravenous and oral administration in male rhesus macaques (Macaca mulatta)

Recently, tramadol and its active metabolite, O-desmethyltramadol (M1), have been studied as analgesic agents in various traditional veterinary species (e.g. dogs, cats, etc.). This study explores the pharmacokinetics of tramadol and M1 after intravenous (IV) and oral (PO) administration in rhesus m...

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Publicado en:J Vet Pharmacol Ther
Main Authors: Kelly, Kristi R., Pypendop, Bruno H., Christe, Kari L.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461566/
https://ncbi.nlm.nih.gov/pubmed/25488714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvp.12194
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