Formulation and Evaluation of Biodegradable Nanoparticles for the Oral Delivery of Fenretinide

Fenretinide is an anticancer drug with low water solubility and poor bioavailability. The goal of this study was to develop biodegradable polymeric nanoparticles of fenretinide with the intent of increasing its apparent aqueous solubility and intestinal permeability. Three biodegradable polymers wer...

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Udgivet i:Eur J Pharm Sci
Main Authors: Graves, Richard A., Ledet, Grace A., Glotser, Elena Y., Mitchner, Demaurian M., Bostanian, Levon A., Mandal, Tarun K.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461492/
https://ncbi.nlm.nih.gov/pubmed/25933716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2015.04.024
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