Structure–activity studies of Ti(IV) complexes: aqueous stability and cytotoxic properties in colon cancer HT-29 cells

As part of our research efforts in the area of titanium-based antitumor agents, we have investigated the cytotoxic activity of [Ti(4)(maltolato)(8)(μ-O)(4)], (Cp-R)(2)TiCl(2) and (Cp-R)CpTiCl(2) (R = CO(2)CH(3) and CO(2)CH(2)CH(3)), and three water-soluble titanocene–amino acid complexes—[Cp(2)Ti(aa...

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Bibliographic Details
Published in:J Biol Inorg Chem
Main Authors: Hernández, Ramón, Lamboy, José, Gao, Li Ming, Matta, Jaime, Román, Félix R., Meléndez, Enrique
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461444/
https://ncbi.nlm.nih.gov/pubmed/18288505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-008-0353-z
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