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Crystallographic study of a novel DNA-binding domain of human HLTF involved in the template-switching pathway to avoid the replication arrest caused by DNA damage

HLTF is a pivotal protein in the template-switching pathway that allows DNA synthesis to continue even in the presence of DNA damage by utilizing a newly synthesized undamaged strand as a template. HLTF has a novel DNA-binding domain termed HIRAN that has been recently found in various proteins, alt...

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Dades bibliogràfiques
Publicat a:Acta Crystallogr F Struct Biol Commun
Autors principals: Ikegaya, Yuzu, Hara, Kodai, Hishiki, Asami, Yokoyama, Hideshi, Hashimoto, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461327/
https://ncbi.nlm.nih.gov/pubmed/26057792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15005907
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