Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease

The complexity of clinical manifestations commonly observed in autoimmune disorders poses a major challenge to genetic studies of such diseases. Systemic lupus erythematosus (SLE) affects humans as well as other mammals, and is characterized by the presence of antinuclear antibodies (ANA) in patient...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Wilbe, Maria, Kozyrev, Sergey V., Farias, Fabiana H. G., Bremer, Hanna D., Hedlund, Anna, Pielberg, Gerli R., Seppälä, Eija H., Gustafson, Ulla, Lohi, Hannes, Carlborg, Örjan, Andersson, Göran, Hansson-Hamlin, Helene, Lindblad-Toh, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461293/
https://ncbi.nlm.nih.gov/pubmed/26057447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005248
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