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TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase
Polymerase basic protein 1 (PB1) is the catalytic core of the influenza A virus (IAV) RNA polymerase complex essential for viral transcription and replication. Understanding the intrinsic mechanisms which block PB1 function could stimulate development of new anti-influenza therapeutics. Affinity pur...
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Publicado no: | PLoS Pathog |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461266/ https://ncbi.nlm.nih.gov/pubmed/26057645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004960 |
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