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The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans

We recently proposed a DNA replication–based mechanism of fork stalling and template switching (FoSTeS) to explain the complex genomic rearrangements associated with a dysmyelinating central nervous system disorder in humans(1). The FoSTeS mechanism has been further generalized and molecular mechani...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Zhang, Feng, Khajavi, Mehrdad, Connolly, Anne M, Towne, Charles F, Batish, Sat Dev, Lupski, James R
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461229/
https://ncbi.nlm.nih.gov/pubmed/19543269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.399
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