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Structure and Function of the 3′ Terminal Six Nucleotides of the West Nile Virus Genome in Viral Replication

Using a self-replicating reporting replicon of West Nile (WN) virus, we performed a mutagenesis analysis to define the structure and function of the 3′-terminal 6 nucleotides (nt) (5′-GGAUCU(OH)-3′) of the WN virus genome in viral replication. We show that mutations of nucleotide sequence or base pa...

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Autors principals: Tilgner, Mark, Shi, Pei-Yong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC446100/
https://ncbi.nlm.nih.gov/pubmed/15254187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.15.8159-8171.2004
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