Clcn5 Knockout Mice Exhibit Novel Immunomodulatory Effects and Are More Susceptible to Dextran Sulfate Sodium-Induced Colitis

Although the intracellular Cl(−)/H(+) exchanger Clc-5 is expressed in apical intestinal endocytic compartments, its pathophysiological role in the gastrointestinal tract is unknown. In light of recent findings that CLC-5 is downregulated in active ulcerative colitis (UC), we tested the hypothesis th...

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Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Alex, Philip, Ye, Mei, Zachos, Nicholas C., Sipes, Jennifer, Nguyen, Thuan, Suhodrev, Maxim, Gonzales, Liberty, Arora, Zubin, Zhang, Ting, Centola, Michael, Guggino, Sandra E., Li, Xuhang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460988/
https://ncbi.nlm.nih.gov/pubmed/20181886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901657
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