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Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei

De novo synthesis of threonine from aspartate occurs via the β-aspartyl phosphate pathway in plants, bacteria and fungi. However, the Trypanosoma brucei genome encodes only the last two steps in this pathway: homoserine kinase (HSK) and threonine synthase. Here, we investigated the possible roles fo...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Ong, Han B, Lee, Wai S, Patterson, Stephen, Wyllie, Susan, Fairlamb, Alan H
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460637/
https://ncbi.nlm.nih.gov/pubmed/25367138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12853
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