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Genetically Engineered Pig Models for Human Diseases
Although pigs are used widely as models of human disease, their utility as models has been enhanced by genetic engineering. Initially, transgenes were added randomly to the genome, but with the application of homologous recombination, zinc finger nucleases, and transcription activator-like effector...
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| Publicado en: | Annu Rev Anim Biosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460601/ https://ncbi.nlm.nih.gov/pubmed/25387017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-animal-031412-103715 |
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