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Rapid molecular evolution across amniotes of the IIS/TOR network

The insulin/insulin-like signaling and target of rapamycin (IIS/TOR) network regulates lifespan and reproduction, as well as metabolic diseases, cancer, and aging. Despite its vital role in health, comparative analyses of IIS/TOR have been limited to invertebrates and mammals. We conducted an extens...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: McGaugh, Suzanne E., Bronikowski, Anne M., Kuo, Chih-Horng, Reding, Dawn M., Addis, Elizabeth A., Flagel, Lex E., Janzen, Fredric J., Schwartz, Tonia S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460498/
https://ncbi.nlm.nih.gov/pubmed/25991861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419659112
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