GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol

G protein-gated inwardly rectifying potassium (GIRK) channels are critical regulators of neuronal excitability and can be directly activated by ethanol. Constitutive deletion of the GIRK3 subunit has minimal phenotypic consequences, except in response to drugs of abuse. Here we investigated how the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Herman, Melissa A., Sidhu, Harpreet, Stouffer, David G., Kreifeldt, Max, Le, David, Cates-Gatto, Chelsea, Munoz, Michaelanne B., Roberts, Amanda J., Parsons, Loren H., Roberto, Marisa, Wickman, Kevin, Slesinger, Paul A., Contet, Candice
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460485/
https://ncbi.nlm.nih.gov/pubmed/25964320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416146112
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