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DNA methylation of BDNF as a biomarker of early-life adversity

Early-life adversity increases the risk for psychopathology in later life. The underlying mechanism(s) is unknown, but epigenetic variation represents a plausible candidate. Early-life exposures can disrupt epigenetic programming in the brain, with lasting consequences for gene expression and behavi...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Kundakovic, Marija, Gudsnuk, Kathryn, Herbstman, Julie B., Tang, Deliang, Perera, Frederica P., Champagne, Frances A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460453/
https://ncbi.nlm.nih.gov/pubmed/25385582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408355111
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