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KCC2 regulates actin dynamics in dendritic spines via interaction with β-PIX

Chloride extrusion in mature neurons is largely mediated by the neuron-specific potassium-chloride cotransporter KCC2. In addition, independently of its chloride transport function, KCC2 regulates the development and morphology of dendritic spines through structural interactions with the actin cytos...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Llano, Olaya, Smirnov, Sergey, Soni, Shetal, Golubtsov, Andrey, Guillemin, Isabelle, Hotulainen, Pirta, Medina, Igor, Nothwang, Hans Gerd, Rivera, Claudio, Ludwig, Anastasia
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460141/
https://ncbi.nlm.nih.gov/pubmed/26056138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201411008
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