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Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control

Primary cilia are sensory organelles that harbor various receptors such as G protein-coupled receptors (GPCRs). We analyzed subcellular localization of 138 non-odorant GPCRs. We transfected GPCR expression vectors into NIH3T3 cells, induced ciliogenesis by serum starvation, and observed subcellular...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Omori, Yoshihiro, Chaya, Taro, Yoshida, Satoyo, Irie, Shoichi, Tsujii, Toshinori, Furukawa, Takahisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459993/
https://ncbi.nlm.nih.gov/pubmed/26053317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128422
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