Characterizing HSF1 Binding and Post-Translational Modifications of hsp70 Promoter in Cultured Cortical Neurons: Implications in the Heat-Shock Response

Causes of lower induction of Hsp70 in neurons during heat shock are still a matter of debate. To further inquire into the mechanisms regulating Hsp70 expression in neurons, we studied the activity of Heat Shock Factor 1 (HSF1) and histone posttranslational modifications (PTMs) at the hsp70 promoter...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gómez, Andrea V., Córdova, Gonzalo, Munita, Roberto, Parada, Guillermo E., Barrios, Álvaro P., Cancino, Gonzalo I., Álvarez, Alejandra R., Andrés, María E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459960/
https://ncbi.nlm.nih.gov/pubmed/26053851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129329
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