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Resveratrol restored Nrf2 function, reduced renal inflammation, and mitigated hypertension in spontaneously hypertensive rats

Compelling evidence supports the role of oxidative stress and renal interstitial inflammation in the pathogenesis of hypertension. Resveratrol is a polyphenolic stilbene, which can lower oxidative stress by activating the transcription factor nuclear factor-E(2)-related factor-2 (Nrf2), the master r...

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Bibliografski detalji
Izdano u:Am J Physiol Regul Integr Comp Physiol
Glavni autori: Javkhedkar, Apurva A., Quiroz, Yasmir, Rodriguez-Iturbe, Bernardo, Vaziri, Nosratola D., Lokhandwala, Mustafa F., Banday, Anees A.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459926/
https://ncbi.nlm.nih.gov/pubmed/25761698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00308.2014
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