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Resveratrol restored Nrf2 function, reduced renal inflammation, and mitigated hypertension in spontaneously hypertensive rats

Compelling evidence supports the role of oxidative stress and renal interstitial inflammation in the pathogenesis of hypertension. Resveratrol is a polyphenolic stilbene, which can lower oxidative stress by activating the transcription factor nuclear factor-E(2)-related factor-2 (Nrf2), the master r...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Javkhedkar, Apurva A., Quiroz, Yasmir, Rodriguez-Iturbe, Bernardo, Vaziri, Nosratola D., Lokhandwala, Mustafa F., Banday, Anees A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459926/
https://ncbi.nlm.nih.gov/pubmed/25761698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00308.2014
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