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Non-Sirtuin Histone Deacetylases in the Control of Cardiac Aging

Histone deacetylases (HDACs) catalyze removal of acetyl-groups from lysine residues within nucelosomal histone tails and thousands of non-histone proteins. The 18 mammalian HDACs are grouped into four classes. Class I, II and IV HDACs employ zinc as a co-factor for catalytic activity, while class II...

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Publicado en:J Mol Cell Cardiol
Autores principales: Ferguson, Bradley S., McKinsey, Timothy A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459895/
https://ncbi.nlm.nih.gov/pubmed/25791169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.03.010
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