Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing

BACKGROUND: High resolution molecular studies have demonstrated that the clonal acquisition of gene mutations is an important mechanism that may promote rapid disease progression and drug resistance in chronic lymphocytic leukemia (CLL). Therefore, the early and sensitive detection of such mutations...

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書誌詳細
出版年:PLoS One
主要な著者: Vollbrecht, Claudia, Mairinger, Fabian Dominik, Koitzsch, Ulrike, Peifer, Martin, Koenig, Katharina, Heukamp, Lukas Carl, Crispatzu, Giuliano, Wilden, Laura, Kreuzer, Karl-Anton, Hallek, Michael, Odenthal, Margarete, Herling, Carmen Diana, Buettner, Reinhard
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459702/
https://ncbi.nlm.nih.gov/pubmed/26053404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129544
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