Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing

BACKGROUND: High resolution molecular studies have demonstrated that the clonal acquisition of gene mutations is an important mechanism that may promote rapid disease progression and drug resistance in chronic lymphocytic leukemia (CLL). Therefore, the early and sensitive detection of such mutations...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vollbrecht, Claudia, Mairinger, Fabian Dominik, Koitzsch, Ulrike, Peifer, Martin, Koenig, Katharina, Heukamp, Lukas Carl, Crispatzu, Giuliano, Wilden, Laura, Kreuzer, Karl-Anton, Hallek, Michael, Odenthal, Margarete, Herling, Carmen Diana, Buettner, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459702/
https://ncbi.nlm.nih.gov/pubmed/26053404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129544
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