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Optimization of sequence alignments according to the number of sequences vs. number of sites trade-off

BACKGROUND: Comparative analysis of homologous sequences enables the understanding of evolutionary patterns at the molecular level, unraveling the functional constraints that shaped the underlying genes. Bioinformatic pipelines for comparative sequence analysis typically include procedures for (i) a...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Dutheil, Julien Y, Figuet, Emeric
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459672/
https://ncbi.nlm.nih.gov/pubmed/26055961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0619-8
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