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Optimization of sequence alignments according to the number of sequences vs. number of sites trade-off

BACKGROUND: Comparative analysis of homologous sequences enables the understanding of evolutionary patterns at the molecular level, unraveling the functional constraints that shaped the underlying genes. Bioinformatic pipelines for comparative sequence analysis typically include procedures for (i) a...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Dutheil, Julien Y, Figuet, Emeric
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459672/
https://ncbi.nlm.nih.gov/pubmed/26055961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0619-8
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