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Exploring the Role of Receptor Flexibility in Structure-Based Drug Discovery

The proper understanding of biomolecular recognition mechanisms that take place in a drug target is of paramount importance to improve the efficiency of drug discovery and development. The intrinsic dynamic character of proteins has a strong influence on biomolecular recognition mechanisms and model...

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Detalles Bibliográficos
Publicado en:Biophys Chem
Main Authors: Feixas, Ferran, Lindert, Steffen, Sinko, William, McCammon, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459653/
https://ncbi.nlm.nih.gov/pubmed/24332165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2013.10.007
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