Somatic DNA Hypomethylation in H. pylori-Associated High-Risk Gastritis and Gastric Cancer: Enhanced Somatic Hypomethylation Associates with Advanced Stage Cancer

OBJECTIVES: Helicobacter pylori-related high-risk gastritis (HRG) is a severe risk factor for gastric cancer (GC). The link between HRG and long-term risk for GC may involve genetic and epigenetic alterations underlying a field defect, i.e. a region of the mucosa prone to cancer development. Global...

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Leodolter, Andreas, Alonso, Sergio, González, Beatriz, Ebert, Matthias P, Vieth, Michael, Röcken, Christoph, Wex, Thomas, Peitz, Ullrich, Malfertheiner, Peter, Perucho, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459532/
https://ncbi.nlm.nih.gov/pubmed/25928808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2015.14
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