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Involvement of neuronal β(2) subunit-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal: Implications for pharmacotherapies

WHAT IS KNOWN AND OBJECTIVE: Tobacco smoking remains a major health problem. Nicotine binds to nicotinic acetylcholine receptors (nAChRs), which can cause addiction and withdrawal symptoms upon cessation of nicotine administration. Pharmacotherapies for nicotine addiction target brain alterations th...

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Detalhes bibliográficos
Publicado no:J Clin Pharm Ther
Main Authors: Simmons, Steven J., Gould, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459499/
https://ncbi.nlm.nih.gov/pubmed/24828779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcpt.12171
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