Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer’s disease

BACKGROUND: Heritability of Alzheimer’s disease (AD) is estimated at 74% and genetic contributors have been widely sought. The ε4 allele of apolipoprotein E (APOE) remains the strongest common risk factor for AD, with numerous other common variants contributing only modest risk for disease. Variabil...

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Detalhes bibliográficos
Publicado no:BMC Neurol
Main Authors: Yokoyama, Jennifer S, Bonham, Luke W, Sears, Renee L, Klein, Eric, Karydas, Anna, Kramer, Joel H, Miller, Bruce L, Coppola, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459447/
https://ncbi.nlm.nih.gov/pubmed/25880661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-015-0304-6
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