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Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells

BACKGROUND: In many cells, bile acids (BAs) have a multitude of effects, some of which may be mediated by specific receptors such the TGR5 or FXR receptors. In pancreas systemic BAs, as well as intra-ductal BAs from bile reflux, can affect pancreatic secretion. Extracellular ATP and purinergic signa...

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Bibliografske podrobnosti
izdano v:Cell Commun Signal
Main Authors: Kowal, Justyna M., Haanes, Kristian A., Christensen, Nynne M., Novak, Ivana
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459444/
https://ncbi.nlm.nih.gov/pubmed/26050734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0107-9
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