Epigenetic memory gained by priming with osteogenic induction medium improves osteogenesis and other properties of mesenchymal stem cells

Mesenchymal stem cells (MSCs) are highly plastic cells that are able to transdifferentiate or dedifferentiate under appropriate conditions. In the present study, we reported here that after in vitro induction of osteogenic differentiation, MSCs could be reverted to a primitive stem cell population (...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Rui, Yunfeng, Xu, Liangliang, Chen, Rui, Zhang, Ting, Lin, Sien, Hou, Yonghui, Liu, Yang, Meng, Fanbiao, Liu, Zhenqing, Ni, Ming, Sze Tsang, Kam, Yang, Fuyuan, Wang, Chen, Chang Chan, Hsiao, Jiang, Xiaohua, Li, Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459169/
https://ncbi.nlm.nih.gov/pubmed/26053250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11056
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